Tagged explore

uBiome Seeks Citizen Scientists to Explore Smokings Effect on Mouth Bacteria


uBiome logo


Although tobacco use in the United States is in slow decline, almost one in five adults is a smoker. While a great deal has been learned over the past fifty years about smoking’s serious health implications, it has only recently become feasible to investigate its impact on the oral microbiome. Biotech startup uBiome is giving smokers, ex-smokers, and non-smokers the chance to contribute to important research while also receiving their individual data showing the bacterial composition of their own mouth. Study participants will get a free at-home, mail-in mouth testing kit. They will also learn how their microbiome compares to those of other smokers, non-smokers, and ex-smokers.

How to take part in the study: http://ubiome.com/smoking

The microbiome consists of the bacteria living in and on the human body, making up between three and six pounds of an individual’s overall weight. Bacteria can be both helpful and harmful. They play a crucial role in digesting food and synthesizing vitamins. However, they also contribute to serious issues such as autoimmune disorders, diabetes, heart conditions, bowel conditions, and skin conditions. The bacteria which make up the human microbiome are distributed across many different parts of the body – in the gut, ears, nose, genitals or mouth, for instance. The mouth alone can be home to around 1,000 different bacterial species.

Oral bacteria can cause tooth decay and gum disease, with figures showing that nearly 42 percent of periodontitis (gum disease) in the United States is attributable to tobacco smoking. There may be other links between smoking and the microbiome. For example a recent study by University Hospital Zurich suggested that the gut microbiomes of ex-smokers differ from those of smokers in a way which might partly account for the weight-gain often seen when people stop smoking. Potential weight-gain is a frequently cited reason for smokers refusing to give up, so understanding more about the interrelationship between bacteria, smoking, and weight change would be invaluable.

Jessica Richman, co-founder and CEO of uBiome, says the tobacco smoking study has significant potential. “Despite the known health risks, about 42 million Americans smoke. One way or another we’re all affected by smoking. Everyone either knows a smoker or is one themselves. We need to know more than we do, so this crucial study will shine a light on some of the unknowns. What difference does it make to the oral microbiome, for instance, if someone took up smoking as a teenager rather than coming to it later in life?”

Almost eighteen of every 100 U.S. adults aged 18 years or older currently smoke cigarettes. Although smoking rates in the U.S. have halved since 1964, the rate of decline has slowed. Smoking dropped from nearly 21 of every 100 adults in 2005 to nearly 18 of every 100 adults in 2013. Cigarette smoking is the leading cause of preventable disease and death in the United States, accounting for more than 480,000 deaths every year, or 1 in 5 of all deaths.

Dr. Zachary Apte, CTO and co-founder of uBiome, says the oral microbiome samples from smokers, ex-smokers and non-smokers will be scrutinized in the company’s state of the art laboratory. “Just ten years ago it would have cost millions of dollars to analyze just one single person’s microbiome. Our sequencing service, based on research from the NIH Human Microbiome Project, can now do it for $ 89. For the first time, this makes large-scale research like uBiome’s new smoking study possible.”

uBiome’s mission is to use big data to understand the human microbiome by giving consumers the power to learn about their bodies, perform experiments, and see how current research studies apply to them. uBiome was launched in 2012 by UCSF scientists and Stanford and Cambridge technologists after a crowd-funding campaign raised over $ 350,000 from citizen scientists, roughly triple the initial goal. uBiome is now funded by Andreesen Horowitz, Y Combinator, and other leading angel investors.

Those interested in participating in the uBiome tobacco smoking study and getting a free mouth microbiome kit can find details here: http://ubiome.com/smoking

Contact:

Alexandra Carmichael

alexandra(at)ubiome(dot)com

Ph: +1 415-691-7291

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Enjoy urban architecture, explore angles, feel the materials and sense the life lines in an urban setting! Thanks my friends!:)

A few nice Interest Rates images I found:

Enjoy urban architecture, explore angles, feel the materials and sense the life lines in an urban setting! Thanks my friends!:)
Interest Rates
Image by UggBoy♥UggGirl [ PHOTO // WORLD // TRAVEL ]
Click here – see urban life lines – on black – more details on view! Enjoy!

Urban design

Urban design concerns the arrangement, appearance and functionality of towns and cities, and in particular the shaping and uses of urban public space. It has traditionally been regarded as a disciplinary subset of urban planning, landscape architecture, or architecture and in more recent times has been linked to emergent disciplines such as landscape urbanism. However, with its increasing prominence in the activities of these disciplines, it is better conceptualised as a design practice that operates at the intersection of all three, and requires a good understanding of a range of others besides, such as urban economics, political economy and social theory.

Urban design theory deals primarily with the design and management of public space (i.e. the ‘public environment’, ‘public realm’ or ‘public domain’), and the way public places are experienced and used. Public space includes the totality of spaces used freely on a day-to-day basis by the general public, such as streets, plazas, parks and public infrastructure. Some aspects of privately owned spaces, such as building facades or domestic gardens, also contribute to public space and are therefore also considered by Urban design theory. Important writers on, and advocates for, urban design theory include Christopher Alexander, Michael E. Arth, Edmund Bacon, Ian Bentley,[1]Peter Calthorpe, Alex Krieger, Gordon Cullen, Andres Duany, Jane Jacobs, Jan Gehl, Kevin Lynch, Roger Montgomery, Aldo Rossi, Colin Rowe, Robert Venturi, William H. Whyte, Bill Hillier, and Elizabeth Plater-Zyberk.

While the two fields are closely related, ‘urban design’ differs from ‘urban planning’ in its focus on physical improvement of the public environment, whereas the latter tends, in practice, to focus on the management of private development through established planning methods and programs, and other statutory development controls.
BY
en.wikipedia.org/wiki/Urban_design

30 St Mary Axe London known as The Gherkin…

30 St Mary Axe, also known as the Gherkin and the Swiss Re Building, is a skyscraper in London’s main financial district, the City of London, completed in December 2003 and opened at the end of May 2004. With 40 floors, the tower is 180 metres (591 ft) tall, and stands on the former site of the Baltic Exchange building, which was severely damaged on 10 April 1992 by the explosion of a bomb placed by the Provisional IRA.

After the plans to build the Millennium Tower were dropped, the current building was designed by Norman Foster, his then business partner Ken Shuttleworth and Arup engineers, and was erected by Skanska in 2001–2003.
BY
en.wikipedia.org/wiki/Swiss_Re_Tower

MODERN LIFE HAS DIVERSE FORMS AROUND THE WORLD, WE SHOULD EXPLORE, HOWEVER ONE OF THE MAIN CONNECTORS IS THE ARCHITECTURE IN OUR CITIES WE VISIT AND LOVE! THE ID OF ANY CITY IS THE HERITAGE, PRESENT AND THE FUTURE OF INTEGRATING ITS PEOPLE / INHABITANTS THROUGH MANMADE OBJECTS D’ ART AND ARCHITECTURE PLAYS A CRUCIAL PART IN BRINGING PEOPLE TOGETHER IN A MEANINGFUL WAY! ENJOY!

[4] The architecture which surrounds us holds many secrets of beauty, often overlooked, now experience a closer encounter of the urban kind! Enjoy the tour as you look up!:)
Interest Rates
Image by UggBoy♥UggGirl [ PHOTO // WORLD // TRAVEL ]
View On Black

Skyscraper

A skyscraper is a tall, continuously habitable building. There is no official definition or height above which a building may clearly be classified as a skyscraper. Most cities define the term empirically; even a building of 80 meters (262 feet) may be considered a skyscraper if it protrudes above its built environment and changes the overall skyline.
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en.wikipedia.org/wiki/Skyscraper

Perspectivism

Perspectivism is the philosophical view developed by Friedrich Nietzsche that all ideations take place from particular perspectives. This means that there are many possible conceptual schemes, or perspectives in which judgment of truth or value can be made. This implies that no way of seeing the world can be taken as definitively "true", but does not necessarily entail that all perspectives are equally valid.
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en.wikipedia.org/wiki/Perspectivism

THE PERSPECTIVE IN LIFE DEPENDS OFTEN ON THE THINGS IN WHICH WE BELIEVE IN AND FIND WORTH DOING IN A PHYSICAL WAY OR PSYCHOLOGIAL WAY! PERSPECTIVE IS UNDERSTANDING AND NEEDS TIME TO DEVELOP, BUT WHEN ITS THERE IT OPENS UP NEW HORIZON! LOOK UP AND ENJOY SOME NEW PERSPECTIVE IN LIFE! THE UPWARD LIFT AWAITS!

[5] The architecture which surrounds us holds many secrets of beauty, often overlooked, now experience a closer encounter of the urban kind! Enjoy the tour as you look up!:)
Interest Rates
Image by UggBoy♥UggGirl [ PHOTO // WORLD // TRAVEL ]
View On Black

Skyscraper

A skyscraper is a tall, continuously habitable building. There is no official definition or height above which a building may clearly be classified as a skyscraper. Most cities define the term empirically; even a building of 80 meters (262 feet) may be considered a skyscraper if it protrudes above its built environment and changes the overall skyline.
BY
en.wikipedia.org/wiki/Skyscraper

Character (arts)

A character is the representation of a person in a narrative or dramatic work of art (such as a novel, play, or film). Derived from the ancient Greek word kharaktêr (χαρακτήρ), the earliest use in English, in this sense, dates from the Restoration, although it became widely used after its appearance in Tom Jones in 1749. From this, the sense of "a part played by an actor" developed. Character, particularly when enacted by an actor in the theatre or cinema, involves "the illusion of being a human person." Since the end of the 18th century, the phrase "in character" has been used to describe an effective impersonation by an actor. Since the 19th century, the art of creating characters, as practiced by actors or writers, has been called characterization.

A character who stands as a representative of a particular class or group of people is known as a type. Types include both stock characters and those that are more fully individualized. The characters in Henrik Ibsen’s Hedda Gabler (1891) and August Strindberg’s Miss Julie (1888), for example, are representative of specific positions in the social relations of class and gender, such that the conflicts between the characters reveal ideological conflicts.

The study of a character requires an analysis of its relations with all of the other characters in the work. The individual status of a character is defined through the network of oppositions (proairetic, pragmatic, linguistic, proxemic ) that it forms with the other characters. The relation between characters and the action of the story shifts historically, often miming shifts in society and its ideas about human individuality, self-determination, and the social order.
BY
en.wikipedia.org/wiki/Character_(arts)

CHARCTER IS OFTEN MISJUDGED AS SOMETHING WE SEE ON THE FIRST TIME ON SOMEONE OR ON SOME OBJECT, LIKE A BUILDING! BUT LOOK CLOSER AND IT GETS MORE COMPLICATED BY THE MINUTE WE REALIZE THAT EVEN A CHARACTER WHICH SEEMS UNATTRACTIVE TO US CAN HAVE HIDDEN DEPTH, WE CONVIENTLY OVERLOOK IN A FAST PACED WORLD! SO TAKE YOUR TIME, LEARN THE BACKGROUND, BUILT A SOLID FOUNDATION AND CREATE YOUR VERY OWN VAULT OF CHARACTERISTICAL KNOWLEDGE WHICH WONT LET YOU DOWN! JUST LOOK UP!